DSpace Community:
http://ir.lib.seu.ac.lk/handle/123456789/177
2024-03-28T23:57:11ZSafezone: an android based mobile app for university students to prevent violence and ragging
http://ir.lib.seu.ac.lk/handle/123456789/7012
Title: Safezone: an android based mobile app for university students to prevent violence and ragging
Authors: Rathnayaka, R. M. C. J. S.; Akmal Jahan, M. A. C.
Abstract: Ragging, a practice involving the hazing of new students by senior students, can result
in various negative outcomes, including mental, physical, and verbal abuse. To address
this issue, we need a mechanism to secretly inform the officials when an incident
happens to safeguards students from ragging incidents. This project aims to design a
mobile app dedicated to enhancing security alert systems for university students. Our
study focuses on creating an application that provides protection for newly entered
university students, specifically against ragging incidents. By adopting this app,
students can easily and secretly share their current location and send an alert via SMS to
required officials. One of the key advantages of this prototype is the ability to report
incidents anonymously without revealing any personal information like phone numbers
or names. By pressing a single button, this prototype allows students to share their
current location and send SMS alerts. This app utilizes OpenAPI for secure data
exchange, alongside the Google Maps API for location services and the Android SMS
API for alert delivery. The is developed using Android Studio by utilizing an Android
mobile device to send location-based SMS alerts within few minutes to security people,
so that they can track the victim casually and prevent any dangerous harm to the
victims. The functionality of this prototype is tested with 50 users, demonstrating high
accuracy in location sharing and positive user feedback regarding its anonymity and
ease of use. Further, we have designed the app to be adaptable for various locations and
platforms. By emphasizing the importance of students’ safety and utilizing technology,
this prototype offers a solution to address the issue of ragging incidents in universities.
Also, will plan to collaborate with universities to integrate Safe Zone with existing
security systems and promote it as an official safety resource, conduct user testing with
the diverse group of university students. This will allow us to refine the app’s usability,
effectiveness and user experience based on real user feedback, develop and integrate
advanced safety features such as emergency contacts, real-time tracking, panic buttons
and AI integration for incident detection and continuously improving security and privacy
measures to ensure strong data protection and user anonymity.2023-12-14T00:00:00ZEvaluation of the antibacterial activity of aqueous extracts obtained from the leaves and bark of Punica granatum
http://ir.lib.seu.ac.lk/handle/123456789/7011
Title: Evaluation of the antibacterial activity of aqueous extracts obtained from the leaves and bark of Punica granatum
Authors: Herath, H. M. U. A. K.; Sanchethana, S. G. C.; Shantha, R. M. R. A.; Hasaana, M. N. F.; Jayasuriya, D. D. M.; Bandara, A. W. M. K. K.; Sedara, D. U. P.
Abstract: Plants are a natural source of novel antimicrobials. Fifty percent of new drugs are
derived from plants, as plants contain phytochemicals that have antimicrobial activity.
As many plants have not yet been investigated for antimicrobial activity, it is a good
source for discovering novel antibiotics. In Ayurveda practices, plants are used in the
treatment of wounds and infections. Punica granatum (Delum) has been used in herbal
medicine for ages. However, the medical benefits of these plants have been discussed in
only a few publications. The plant is documented to possess beneficial effects for eye
infections, heart diseases, dysentery, coughs, oedema, worms’ diseases, asthma, skin
diseases, fever, etc. This study aimed to evaluate the antimicrobial activity of aqueous
extracts of the leaves and bark of the Punica granatum plant against Staphylococcus
aureus and Pseudomonas aeruginosa. Staphylococcus aureus and Pseudomonas
aeruginosa were obtained from the biomedical laboratory of Kaatsu International
University. Plant materials were collected from the Colombo district, and authentication
has been obtained from the botany division of the Bandaranayake Memorial Ayurvedic
Research Institute, Nawinna, Maharagama, Sri Lanka. Extractions of plants were
obtained by the decoction method, and a series of concentrations were prepared. The
antibacterial activity of the extracts of the leaves and bark of delum against
Staphylococcus aureus (ATCC 25923) and Pseudomonas aeruginosa (ATCC 27853)
was measured using the agar-well diffusion method. Gentamicin (10 μg/ml) was used
as the positive control. Each assay was done in triplicate. Aqueous extract of leaves
showed the highest antimicrobial activity with inhibition zones of 28.00 ±1.00 mm
(Staphylococcus aureus) and 21.0 and 0±1.00 mm (Pseudomonas aeruginosa), while
bark extract (aqueous) showed 22.33±0.58 mm and 17.67±0.58mm of inhibition zones
against Staphylococcus aureus and Pseudomonas aeruginosa, respectively. Both
Punica granatum leaf and bark aqueous extracts possess antibacterial properties.
Following testing on various clinical isolates, the extracts demonstrate potential for the
development of antibacterial formulations targeting Staphylococcus aureus and
Pseudomonas aeruginosa.2023-12-14T00:00:00ZCytotoxicity determination of aerva lanata methanolic extract using brine shrimp lethality assay for treatment of urinary tract infections
http://ir.lib.seu.ac.lk/handle/123456789/7010
Title: Cytotoxicity determination of aerva lanata methanolic extract using brine shrimp lethality assay for treatment of urinary tract infections
Authors: Fernando, K. M. K.; Ilangage, J. I. M. K.; Ilangakoon, I. A. C. S.; Dissanayaka, D. M. M. K.; Rajapaksha, N. P. D.; Walpola, L. H.; Hettiarachchi, D.
Abstract: Plant toxicity studies play a crucial role in ensuring the safety of herbal medicines,
evaluating potential risks associated with plants. The Brine Shrimp Lethality Assay
(BSLA) is a widely used and cost-effective preliminary screening tool for assessing the
toxicity of various substances, including plant extracts and compounds. Objectives of
this study were to explore innovative methods for assessing the toxicity of methanolic
extract of Aerva lanata using the BSLA for treatment of Urinary Tract Infections and to
provide a foundational understanding of the toxicity of Aerva lanata extract and its
potential implications for medicinal use. In-vitro experimental study was conducted at
KIU laboratory, Koswatte. A. lanata whole plant and its extraction were considered as
the sample used. Concentration of plant extract known to be the independent variable
and Brine shrimp (Artemia salina) mortality as an indicator of extract toxicity was
known to be the dependent variable. Data analysis was carried out using toxicity index
values (LC50) of the Aerva lanata extract were used to find out whether the extract is
toxic or non-toxic. Stock solution was prepared by dissolving 10 mg of plant extract
(soluble in water) in 1 ml of water. Concentrations of 1 mg/ ml, 100 µg/ ml, 10 µg/ ml
and 1 µg/ ml were prepared by serial dilution from the stock solution. 1 ml of prepared
solution was taken into the respect test tubes containing 10 live nauplii of A. salina and
1 ml of seawater. After 24 hours of incubation at 25 o C, the live nauplii were counted in
each test concentration of the tube. Live nauplii were move towards the light source.
The 1% dimethyl sulfoxide without extract was used as a negative control. The results
were recorded as the percentage of mortality after 24 hours and 50% Lethal
Concentration (LC50) values were calculated using Graph Pad prism 9 software. Then
it compared with the toxicity scale of LC 50 < 1000ug/ml is considered toxic and if LC
50 > 1000ug/ml considered as non-toxic. The resulting LC50 was 59.34µg/ml.
Therefore, A. lanata methanolic extract is considered to be toxic since LC 50 <
1000ug/ml; according to the brine shrimp lethality assay. The research on the
cytotoxicity of A. lanata using the brine shrimp lethality assay provided valuable
insights into the safety evaluation of medicinal plant extracts. The study effectively
fulfilled its objectives by demonstrating the potential utility of the brine shrimp lethality
assay in evaluating toxicity of A. lanata plant extract; lay the groundwork for further
comprehensive evaluations, offering promise in the development of safer and more
efficient herbal treatments in traditional medicine.2023-12-14T00:00:00ZPreliminaries
http://ir.lib.seu.ac.lk/handle/123456789/7009
Title: Preliminaries2023-12-14T00:00:00Z