Please use this identifier to cite or link to this item: http://ir.lib.seu.ac.lk/handle/123456789/2381
Title: Anti fungal activity of N-phenylbenzohydroxamic acid against mu cor sp.
Authors: Safeena, M.I.S.
Senthilnithy, R.
Keywords: Hydroxamic acids
Antifungal activity
Mucor sp
Issue Date: 28-Mar-2012
Publisher: Faculty of Applied Science, South Eastern University of Sri Lanka
Citation: Faculty of Applied Science, South Eastern University of Sri Lanka. First Annual Science Research Session 2012
Abstract: Some N-phenylbenzohydroxamic acid derivatives were prepared and their anti fungal activities were explored. The compound was characterized with I H-NMR and IR spectra. There are many hydrodynamic acids prevailing in living organisms. Hydrodynamic acids generally have low toxicities and have a wide spectrum of activities in all types of biological system. The anti fungal activities of the derivatives were studied preliminary against the growth of Mucor sp. by disc method. Different concentrations of acid were tested against the fungi and the growth was observed for 4 days. Nphenylbenzohydroxamic acid was markedly inhibitory to growth of Mucor sp. quantitatively at 10.5 ppm. Activity was apparently not mediated through a release of free hydroxyl-amine and it was directly controlling the growth of the above fungi. This was evidenced by the loss of normal pattern of growth and colour change in the mycelia.
URI: http://ir.lib.seu.ac.lk/handle/123456789/2381
ISBN: 9789556270273
Appears in Collections:ASRS - FAS 2012

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