In vitro T-cell inhibition of Aurasperone –A from a marine derived fungus Aspergillus fonsaceus

Abstract

Aurasperone –A (1) was isolated from the culture broth of a fungus Aspergillus fonsaceus, which was separated from a brown alga along with Adenine (2), Uridine (3) and Phenyl acetic acid (4). Structures of compounds 1-4 were deduced by the spectroscopic data. Compound 1 showed a potential suppressive effect on T-cell proliferation inhibition assay.