Abstract:
Schiff bases are organic compounds and were
first reported by Hugo Schiff in 1864 [1]. These
are usually formed by the condensation of
primary amines with carbonyl compounds.
They have a characteristic group -C=N-, which
are called azomethines. The development of the
new chemotherapeutic Schiff bases is now
attracting the attention of medicinal chemists. It
is known to exhibit a variety of powerful
activities. Due to the presence of carbon-nitrogen double bond in Schiff bases they have
significant biological activities. Such as
antibacterial, antifungal [2], antioxidant [3] and
anti-inflammatory [3] activities.
Succinimides are cyclic imides that have
pharmaceutical applications. Due to the
presence of both carbonyl and methylene
groups, they have high chemical reactivity and
biological activity. Succinimides are
heterocyclic compounds. In recent years,
heterocyclic compounds play an important role
in the development of organic synthesis and
their wide range of applications in the field of
pharmaceuticals, agrochemicals, and veterinary
products [4].
The current study has been conducted on
synthesis of Schiff bases and Succinimide
compounds, to check the purity of all
compounds using thin-layer and column
chromatography, and to evaluate the
antimicrobial activity of each synthesized
compound against pathogenic bacteria and
fungi.
