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http://ir.lib.seu.ac.lk/handle/123456789/3717| Title: | New monoterpenoid by biotransformation of thymoquinone using Aspergillus niger |
| Authors: | Mohammad, M. Y. Haroon, M. H. Choudhary, M. I. |
| Issue Date: | Nov-2018 |
| Publisher: | University of Karachi, Pakistan |
| Series/Report no.: | 2nd International Symposium on Natural Products for the Future (ISNPC-2); |
| Abstract: | Microbial transformation of thymoquinone (5-isopropyl-2-methyI-cycIohexa-2,5-diene-l ,4- dione) ( l) by suspended cell-cultures of the plant pathogenic fungus Aspergillus niger resulted in the production of three metabolites. These metabolites were identified as 5-isopropyl-2- methyl-2,4-cycIohexenone lactone (2), hydroxythymoquinone (3), and 4-hydroxy-2-isopropyl- 5-methylphenol (4) by different spectroscopic methods. Metabolite 2 was found to be a new compound. Compound 4 showed potent antioxidant activity. |
| URI: | http://ir.lib.seu.ac.lk/handle/123456789/3717 |
| Appears in Collections: | Research Articles |
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| 1_0001.jpg | 144.7 kB | JPEG |  View/Open |
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